Francesco Emma Selected Research

Nephrotic Syndrome (Syndrome, Nephrotic)

1/2024	A child with semaphorin 3b-associated membranous nephropathy effectively treated with obinutuzumab after rituximab resistance.
1/2024	A novel flow cytometry panel to identify prognostic markers for steroid-sensitive forms of idiopathic nephrotic syndrome in childhood.
1/2023	Age and memory B cells at baseline are associated with risk of relapse and memory B-cell reappearance following anti-CD20 treatment in pediatric frequently-relapsing/steroid-dependent nephrotic syndrome.
1/2023	A phase I study of autologous mesenchymal stromal cells for severe steroid-dependent nephrotic syndrome.
1/2023	Treatment of idiopathic nephrotic syndrome at onset: a comparison between 8- and 12-week regimens in everyday clinical practice.
1/2023	Outcomes of steroid-resistant nephrotic syndrome in children not treated with intensified immunosuppression.
1/2022	Belimumab for the treatment of children with frequently relapsing nephrotic syndrome: the BELNEPH study.
1/2022	Update on the treatment of steroid-sensitive nephrotic syndrome.
1/2022	Oral Coenzyme Q10 supplementation leads to better preservation of kidney function in steroid-resistant nephrotic syndrome due to primary Coenzyme Q10 deficiency.
1/2022	Variation of the clinical spectrum and genotype-phenotype associations in Coenzyme Q10 deficiency associated glomerulopathy.

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Francesco Emma Research Topics

Disease

34	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2024 - 05/2003
30	Cystinosis 03/2024 - 02/2006
19	Proteinuria 01/2024 - 05/2003
13	Chronic Kidney Failure (Chronic Renal Failure) 11/2021 - 11/2006
10	Renal Insufficiency (Renal Failure) 01/2022 - 06/2003
8	Fanconi Syndrome (Syndrome, Fanconi) 01/2020 - 09/2013
6	Hypertension (High Blood Pressure) 01/2024 - 08/2005
5	Kidney Diseases (Kidney Disease) 01/2023 - 01/2021
5	Rare Diseases (Rare Disease) 12/2021 - 01/2012
5	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2020 - 05/2003
5	Infections 10/2019 - 06/2009
4	Membranous Glomerulonephritis (Membranous Nephropathy) 01/2024 - 03/2015
4	Renal Tubular Acidosis (Distal Renal Tubular Acidosis) 12/2021 - 01/2019
4	Lysosomal Storage Diseases (Lysosomal Storage Disease) 01/2020 - 01/2016
3	IGA Glomerulonephritis (IGA Nephropathy) 11/2023 - 03/2005
3	Acidosis 12/2021 - 07/2014
3	Donnai-Barrow syndrome 08/2021 - 01/2020
3	Atypical Hemolytic Uremic Syndrome 02/2021 - 12/2013
3	Cystinuria 01/2021 - 01/2010
3	Chronic Renal Insufficiency 12/2020 - 03/2016
3	Mitochondrial Diseases (Mitochondrial Disease) 01/2020 - 03/2006
3	Autosomal Dominant Polycystic Kidney (ADPKD) 11/2019 - 03/2016
3	Disease Progression 07/2019 - 05/2007
2	Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia) 01/2024 - 01/2023
2	Glomerulonephritis 12/2023 - 12/2019
2	Hyperparathyroidism 11/2022 - 01/2019
2	Bartter Syndrome (Syndrome, Bartter) 11/2022 - 01/2021
2	Coenzyme Q10 Deficiency 01/2022 - 01/2022
2	Inborn Genetic Diseases (Disease, Hereditary) 12/2021 - 07/2019
2	Alkalosis 01/2021 - 03/2006
2	Acute Kidney Injury (Acute Renal Failure) 01/2021 - 11/2012
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2021 - 01/2015
2	Tetanus 01/2021 - 01/2019
2	Segmental glomerulosclerosis 01/2020 - 01/2006
2	Cysts 07/2019 - 03/2016
2	Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II) 03/2016 - 03/2012
2	Hereditary Nephritis (Alport Syndrome) 05/2013 - 07/2010
2	Dent Disease 10/2009 - 09/2006
1	Hematuria 01/2024
1	Polyuria 01/2024

Drug/Important Bio-Agent (IBA)

24	Cystine (L-Cystine)IBA 01/2024 - 05/2008
15	SteroidsIBA 01/2024 - 05/2003
10	Cysteamine (Mercaptamine)FDA Link 01/2023 - 11/2010
9	Rituximab (Mabthera)FDA Link 01/2024 - 04/2014
7	Prednisone (Sone)FDA LinkGeneric 01/2024 - 01/2017
7	SymportersIBA 11/2021 - 08/2012
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2007
6	AntibodiesIBA 10/2021 - 12/2013
5	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2024 - 09/2004
5	Phosphates (Orthophosphate)IBA 01/2024 - 01/2016
5	Complement System Proteins (Complement)IBA 12/2023 - 12/2013
5	Protons (Proton)IBA 12/2021 - 09/2014
5	SaltsIBA 01/2021 - 09/2005
5	NPHS2 proteinIBA 07/2013 - 05/2003
4	Monoclonal AntibodiesIBA 01/2024 - 01/2017
4	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 01/2017
3	GlucocorticoidsIBA 01/2023 - 05/2008
3	CalciumIBA 11/2022 - 01/2012
3	dirhodium tetraacetate (DRTA)IBA 12/2021 - 01/2019
3	Mycophenolic Acid (Cellcept)FDA LinkGeneric 11/2021 - 03/2005
3	ofatumumab FDA Link 10/2021 - 01/2017
3	Low Density Lipoprotein Receptor-Related Protein-2IBA 08/2021 - 01/2020
3	Immunoglobulin G (IgG)IBA 01/2021 - 03/2015
3	Mitochondrial DNA (mtDNA)IBA 01/2020 - 03/2006
3	Protein Isoforms (Isoforms)IBA 01/2017 - 09/2006
2	Semaphorins (Semaphorin)IBA 01/2024 - 11/2020
2	Antigen-Antibody Complex (Immune Complex)IBA 01/2024 - 11/2020
2	Messenger RNA (mRNA)IBA 01/2024 - 08/2011
2	burosumabIBA 01/2024 - 01/2022
2	Amino Acids FDA Link 09/2022 - 10/2009
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2021
2	coenzyme Q10 (CoQ10)IBA 01/2022 - 05/2016
2	Blood Proteins (Serum Proteins)IBA 01/2022 - 01/2020
2	ubiquinone 6IBA 01/2022 - 01/2022
2	Calcineurin InhibitorsIBA 10/2021 - 10/2017
2	LigandsIBA 08/2021 - 01/2020
2	eculizumab FDA Link 02/2021 - 03/2012
2	AntigensIBA 01/2021 - 12/2019
2	AlkaliesIBA 01/2021 - 01/2010
2	TinIBA 01/2021 - 11/2006
2	Immunoglobulin M (IgM)IBA 01/2021 - 10/2019
2	Neprilysin (Neutral Endopeptidase)IBA 12/2019 - 03/2015
2	Tolvaptan FDA Link 07/2019 - 03/2016
2	Levamisole (Decaris)FDA Link 01/2019 - 01/2018
2	Immunoglobulins (Immunoglobulin)IBA 01/2019 - 03/2016
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2018 - 09/2009
2	ElectrolytesIBA 04/2017 - 07/2014
2	ThrombomodulinIBA 09/2016 - 12/2013
2	CopperIBA 01/2016 - 09/2013
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 08/2005 - 03/2005
1	Vitamin D FDA LinkGeneric 01/2024
1	AntiportersIBA 01/2024
1	obinutuzumabIBA 01/2024
1	Fibroblast Growth Factor-23IBA 01/2024
1	Interleukin-6 (Interleukin 6)IBA 01/2024

Therapy/Procedure

18	Therapeutics 01/2024 - 01/2006
5	Kidney Transplantation 01/2015 - 06/2003
2	Transplantation 01/2020 - 05/2007
2	Renal Dialysis (Hemodialysis) 05/2015 - 09/2013
1	Transition to Adult Care 03/2024